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Activation and Detoxification Enzymes Functions and Implications【電子書籍】 Chang-Hwei Chen

Activation and Detoxification Enzymes Functions and Implications【電子書籍】[ Chang-Hwei Chen ]

ショップ楽天Kobo電子書籍ストア

価格￥13,369

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商品の説明

＜p＞Humans are exposed to foreign compounds such as drugs, household products and environmental chemicals by swallowing or breathing. Also, food is considered a foreign compound. Such foreign compounds can be non-essential and non-functional to life, and commonly are referred to as xenobiotics. Some xenobiotics are not toxic; however, many of them are potentially toxic or become toxic after conversion to metabolic intermediates. A considerable number of foreign compounds belong to non-polar, lipophilic substances. Lipophilic compounds are not soluble in water. Metabolic conversion of lipophilic foreign compounds to facilitate their removal from the body is essentially carried out by biochemical reactions catalyzed by two classes of metabolizing enzymes, namely, activation enzymes and detoxification enzymes.＜/p＞＜p＞Activation enzyme-catalyzed functionalization reaction introduces a functional group to a lipophilic compound. Functionalization modifies many foreign compounds to fo...

Activation and Detoxification Enzymes Functions and Implications【電子書籍】[ Chang-Hwei Chen ]

ショップ楽天Kobo電子書籍ストア

価格￥17,016

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商品の説明

＜p＞This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry. The book will also be valuable to advanced researchers. The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers. This new edition is updated throughout andfeatures completely new chapters o...

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